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Frequently Asked Questions - Answered by a Shoppers Drug Mart Pharmacist

    1. I've been on antidepressants for a week and I don't feel better yet. Should I go back to my doctor?
      The length of time before you start seeing results may vary from person to person. While some people may see results more quickly, it could take up to eight weeks before your symptoms start to ease. In the mean time, stick with your meds and never stop taking your medications without consulting with your Shoppers Drug Mart Pharmacist first - some antidepressants may cause withdrawal effects if you don't wean yourself off them. In the meantime, any side effects should taper off on their own. If after a few weeks, you still find the side effects to be unbearable, talk to your doctor - you may need to change medications or require a dose adjustment.
       
    2. Are all of the various types of antidepressants the same?
      No, there are a number of different classes of antidepressants, each of which affects the neurotransmitters in the brain in different ways. While all are believed to have a similar level of effectiveness, some work better for certain problems than others or make be more effective for some people and not others. How a particular antidepressant worked for a close family member may be an indication of how effective it will be for you, so let your doctor know about any close relative's experience with particular medications. The important thing to know is that if one antidepressant doesn't work for you, or if you are experiencing intolerable side effects, switching to a different antidepressant can make a big difference.
       
    3. I'm thinking about getting pregnant. Do I need to go off my antidepressants?
      This is an important issue to discuss with a healthcare professional, and it is great that you are considering this issue before you start trying to conceive. This is a complicated question to answer because there are risks and benefits to both stopping and staying on medications during a pregnancy, and it's important to weigh the risks and benefits of both. While there is still relatively little information available on the subject, the majority of studies conducted have shown the use of selective serotonin reuptake inhibitors (SSRIs) to be safe for use during pregnancy. There may, however, be a risk of low birth weight associated with using the SSRI fluoxetine in the third trimester. Studies on tricyclic antidepressants did not show an increased risk of miscarriage or birth defects. Because different medications may be safer for you and your baby at this time than others, make sure to speak to your doctor. If you do decide to continue treatment, your doctor may also decide to reduce your dosage.
       
    4. My mother suffers from depression. Am I at risk too?
      Yes, having a family member who suffers from depression does put you at greater risk of depression as well. Researchers at Duke University in the US recently discovered a gene that may pre-dispose individuals to major depression. Researchers have also found a variation in a gene that affects levels of the mood-related neurotransmitter serotonin that can increase your risk of depression following a major stress occurrence in your life. Neurotransmitters are the chemicals which allow nerve cells in the brain to communicate with one another. If you believe you are predisposed to depression, you should know there is no known preventative treatment for depression. But you may be able to influence the number and severity of depressive episodes in your lifetime through treatment such as medication, psychotherapy or a combination of both and lifestyle factors such as diet and exercise.
       
    5. I just got hired for a job that involves night shifts. Will this make me feel more depressed?
      The body has a natural rhythm of sleeping and wakefulness, called the circadian rhythm, which is regulated by exposure to sunlight. Working on the night shift will cause a change in this rhythm, because your altered sleep schedule means you will have less exposure to daylight. This in turn may affect the production of mood-related neurotransmitters, such as serotonin, and may predispose you to depression. Studies show that night workers do have a higher risk of depression. While the exact causes for this link is unclear, working at night may isolate you from friends and family, reducing your support system and further increasing the risk of becoming depressed.
       
    6. I went on medication last year because I had panic attacks during a stressful time at work. The stressful situation has eased. Do I need to stay on my medication?
      This is a decision that you need to make after consulting with your doctor. Many people can go off antidepressants - which are often used to prevent panic attacks - but it must be done according to a plan, by gradually reducing the dose of the medication in order to prevent withdrawal symptoms. It is also important that you know how to spot any signs and symptoms of your anxiety disorder returning.

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